317Clinical effectiveness of mupirocin for preventing S. aureus infections in non-surgical settings: A Meta-analysis
نویسندگان
چکیده
317. Clinical effectiveness of mupirocin for preventing S. aureus infections in non-surgical settings: A Meta-analysis Rajeshwari Nair, MBBS, MPH; Eli Perencevich, MD, MS, FIDSA, FSHEA; Amy Blevins, MALS; Marin Schweizer, PhD; Epidemiology, University of Iowa, Iowa City, IA; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA; Hardin Library for the Health Sciences, University of Iowa, Iowa City, IA; Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA
منابع مشابه
Intranasal mupirocin for reduction of Staphylococcus aureus infections in surgical patients with nasal carriage: a systematic review.
OBJECTIVES The majority of nosocomial Staphylococcus aureus infections originate from the patients' own flora, with nasal carriage of S. aureus before surgical procedures being a risk factor for subsequent infection. The objective of this review was to assess whether intranasal mupirocin treatment of nasal S. aureus carriers before surgery results in a reduction of the post-operative S. aureus ...
متن کاملMupirocin prophylaxis against nosocomial Staphylococcus aureus infections in nonsurgical patients: a randomized study.
BACKGROUND Staphylococcus aureus nasal carriage is a major risk factor for nosocomial S. aureus infection. Studies show that intranasal mupirocin can prevent nosocomial surgical site infections. No data are available on the efficacy of mupirocin in nonsurgical patients. OBJECTIVE To assess the efficacy of mupirocin prophylaxis in preventing nosocomial S. aureus infections in nonsurgical patie...
متن کاملSurgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study.
The objective of this study was to determine whether use of mupirocin nasal ointment for perioperative eradication of Staphylococcus aureus nasal carriage is effective in preventing the development of surgical site infections (SSIs). A randomized, double-blind, placebo-controlled design was used. Either mupirocin or placebo nasal ointment was applied twice daily to 614 assessable patients from ...
متن کاملPreventing surgical-site infections in nasal carriers of Staphylococcus aureus.
BACKGROUND Nasal carriers of Staphylococcus aureus are at increased risk for health care-associated infections with this organism. Decolonization of nasal and extranasal sites on hospital admission may reduce this risk. METHODS In a randomized, double-blind, placebo-controlled, multicenter trial, we assessed whether rapid identification of S. aureus nasal carriers by means of a real-time poly...
متن کاملPreventing surgical site infections: a randomized, open-label trial of nasal mupirocin ointment and nasal povidone-iodine solution.
BACKGROUND Treatment of Staphylococcus aureus colonization before surgery reduces risk of surgical site infection (SSI). The regimen of nasal mupirocin ointment and topical chlorhexidine gluconate is effective, but cost and patient compliance may be a barrier. Nasal povidone-iodine solution may provide an alternative to mupirocin. METHODS We conducted an investigator-initiated, open-label, ra...
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